Blood flow in the cerbral cortex of Tibetan Buddhist meditators was observed using Single Photon Emission Computed Tomography (SPECT), a brain imaging technique which measures metabolic activity in the brain. The results showed a significant increase in activity (P < .05) in the cingulate gyrus, inferior and orbital frontal cortex, as well as the dorsolateral prefrontal cortex and thalamus. The authors speculate a correlated change in the dorsolateral prefrontal cortex and the superior parietal lobe may account for the feeling of an altered sense of space during meditation. (Zach Rowinski 2005-03-05)